SYNERGY PHARMACEUTICALS

CUSIP: 87163930 Class: COM NEW

INGALLS & SNYDER LLC's Holding History (CIK: 0001041885)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 10,000 Value ($000) $27 Avg Close — Range —
Q4 2015
Shares 10,000 Value ($000) $56 Avg Close — Range —
Q3 2015
Shares 10,016 Value ($000) $53 Avg Close — Range —
Q2 2015
Shares 10,000 Value ($000) $83 Avg Close — Range —
Q1 2015
Shares 10,000 Value ($000) $46 Avg Close — Range —
Q4 2014
Shares 10,000 Value ($000) $30 Avg Close — Range —
Q3 2014
Shares 10,000 Value ($000) $27 Avg Close — Range —
Q2 2014
Shares 10,000 Value ($000) $40 Avg Close — Range —